Types of Drugs That Will Kill Your Sexual Interest Birth prevention pills as well as other medicines can dampen desire.(BEATHAN/CORBIS/VEER)If you are making love drive problems, always check your medication case. Several types of prescription medicine can dampen desire. Contraception Some hormone contraception practices such as for example pills and spots increases ladies’ degrees of sex-hormone-binding globulin (SHBG), which falls the total amount of testosterone that’s floating around easily within the bloodstream.